Workshop ASHG2023 > Session 1: Imputation and the Server

Server Links

Michigan Imputation Server

TOPMed Imputation Server

Selected Literature

Das S, Forer L, Schönherr S, Sidore C, Locke AE, Kwong A, Vrieze SI, Chew EY, Levy S, McGue M, Schlessinger D, Stambolian D, Loh PR, Iacono WG, Swaroop A, Scott LJ, Cucca F, Kronenberg F, Boehnke M, Abecasis GR, Fuchsberger C. Next-generation genotype imputation service and methods. Nat Genet. 2016 Oct;48(10):1284-1287. doi: 10.1038/ng.3656.

Das S, Abecasis GR, Browning BL. Genotype Imputation from Large Reference Panels. Annu Rev Genomics Hum Genet. 2018 Aug 31;19:73-96. doi: 10.1146/annurev-genom-083117-021602.

Fuchsberger C, Abecasis GR, Hinds DA. minimac2: faster genotype imputation. Bioinformatics. 2015 Mar 1;31(5):782-4. doi: 10.1093/bioinformatics/btu704. Epub 2014 Oct 22. PMID: 25338720; PMCID: PMC4341061.

Howie B, Fuchsberger C, Stephens M, Marchini J, Abecasis GR. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet. 2012 Jul 22;44(8):955-9. doi: 10.1038/ng.2354. PMID: 22820512; PMCID: PMC3696580.