Scores

We support currently the following PGS repositories out of the box:

PGS-Catalog

We use PGS Catalog as the source of scores for PGS Server (version 19. Jan 2023). the PGS Catalog is an online database that collects and annotates published scores and currently provides access to over 3,900 scores encompassing more than 580 traits.

Samuel A. Lambert, Laurent Gil, Simon Jupp, Scott C. Ritchie, Yu Xu, Annalisa Buniello, Aoife McMahon, Gad Abraham, Michael Chapman, Helen Parkinson, John Danesh, Jacqueline A. L. MacArthur and Michael Inouye. The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation. Nature Genetics. doi: 10.1038/s41588-021-00783-5 (2021).

Cancer-PRSweb

Collection of scores for major cancer traits.

Fritsche LG, Patil S, Beesley LJ, VandeHaar P, Salvatore M, Ma Y, Peng RB, Taliun D, Zhou X, Mukherjee B: Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. Am J Hum Genet 2020, 107(5):815-836.

ExPRSweb

Collection of scores for common health-related exposures like body mass index or alcohol consumption.

Ma Y, Patil S, Zhou X, Mukherjee B, Fritsche LG: ExPRSweb: An online repository with polygenic risk scores for common health-related exposures. Am J Hum Genet 2022, 109(10):1742-1760.